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A very small percentage of animals will become aggressive on Acepromazine.
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If using this medication for a long car or plane trip a trial dosing is recommended at home a few days before to make sure the pet handles it ok. It needs to be used with caution in older animals because it lowers blood pressure. It does cause significant sedation so physical activity is usually out of the question for the day. It is great for long car rides or plane trips. Acepromazine is a tranquilizer but also helps prevent nausea associated with motion sickness. Valium needs to be used with caution in cats as some cats can develop liver disease as a rare but serious side effect. Valium can cause sedation and increased appetite. This medication is indicated where anxiety is a big factor. Another option is Diazepam, also know as Valium. Side effects include sedation and rarely hyperactivity. Benadryl is a safe and inexpensive option. If behavior modification doesn’t work there are several different medications to chose from. Once the pet sees that nothing bad is going to happen you can gradually increase the amount of time in the car and begin taking short drives working your way up to a drive to the vet or groomer. This can be done by bringing the pet to the car for short periods of time. This involves desensitization or getting the pet used to the car. So what can we do about it? In cases where anxiety is the suspect cause you can try behavior modification. Motion sickness occurs when conflicting signals from the eyes and inner ear are sent to the brain.
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Does your pet get motion sickness during car rides? The signs of motion sickness in dogs and cats are drooling, and vomiting. Sometimes it is accompanied by anxious behaviors such as excess vocalization, pacing and panting.